Table 1.

Top 10 down- and upregulated genes in AGE-treated retinal endothelial cells compared with untreated cells

ID	Symbol	Fold change	P	Adjusted P
Downregulated
NM_014762	DHCR24	0.170596	5.34E−61	5.69E−58
NM_001001557	GDF6	0.186286	2.43E−33	4.40E−31
NM_001190481	CLSPN	0.199349	1.33E−31	1.99E−29
NM_001190819	ORC1	0.228472	9.77E−24	6.56E−22
NM_021062	HIST1H2BB	0.235626	3.01E−34	5.97E−32
NM_005192	CDKN3	0.236398	1.85E−19	7.69E−18
NM_001255	CDC20	0.236876	5.86E−40	1.78E−37
NM_003535	HIST1H3J	0.240679	1.06E−11	1.84E−10
NM_005733	KIF20A	0.242997	1.07E−39	3.04E−37
NM_021066	HIST1H2AJ	0.249445	1.34E−21	7.19E−20
Upregulated
NM_000450	SELE	36.68773	3.45E−67	5.89E−64
NM_054110	GALNT15	33.79375	2.20E−69	9.37E−66
NM_002982	CCL2	26.76679	3.75E−160	3.20E−156
NM_020163	SEMA3G	9.93811	4.66E−65	5.75E−62
NM_033439	IL33	9.836069	1.84E−53	1.31E−50
NM_181482	LDLRAD4	8.915839	1.46E−35	3.18E−33
NM_001004439	ITGA11	8.254615	4.06E−38	1.12E−35
NM_006472	TXNIP	7.839528	1.60E−67	3.42E−64
NM_001511	CXCL1	7.620618	3.93E−54	3.05E−51
NM_000201	ICAM1	7.5609	6.04E−69	1.72E−65