Table 1.
Case patients (n = 6) | Control participants (n = 30) | Total cohort (n = 262) | P * | |
---|---|---|---|---|
Sex | ||||
Male | 4 (67) | 16 (53) | 162 (59) | 0.7† |
Female | 2 (33) | 14 (47) | 113 (41) | 0.3† |
Age, years | 11.3 ± 2 | 11.2 ± 2 | 11.5 ± 2 | 0.9† |
Weight, kg | 68.5 ± 26 | 65.8 ± 20 | 66.1 ± 20 | 0.7† |
Height, cm | 152.5 ± 17 | 150.3 ± 13 | 151.1 ± 12 | 0.6† |
BMI, kg/m2 | 28.3 ± 6 | 28.5 ± 5 | 28.3 ± 6 | 0.7† |
BMI percentile | 96.9 ± 4 | 97.5 ± 3 | 96.5 ± 5 | 0.6† |
<85th (normal) | 0 (0) | 0 (0) | 9 (3) | |
≥85th and ≤95th percentile (overweight) | 1 (17) | 4 (13) | 97 (35) | |
≥95th and 120% of 95th percentile (class I obesity) | 3 (50) | 15 (50) | 133 (48) | |
>120% of 95th percentile (class II or III) | 2 (33) | 11 (37) | 80 (30) | |
Tanner stage | 0.1‡ | |||
1 | 3 (50) | 7 (23) | 89 (32) | |
2 | 0 (0) | 8 (27) | 90 (33) | |
3 | 0 (0) | 4 (13) | 36 (13) | |
4 | 6 (20) | 40 (15) | ||
5 | 3 (50) | 5 (17) | 20 (7) | |
Birth weight, kg | 4.0 ± 1.1 | 3.7 ± 0.8 | 3.7 ± 1.1 | 0.7† |
Household education level | 0.2‡ | |||
Lower than high school | 3 (50) | 17 (57) | 187 (68) | |
Completed high school | 0 (0) | 12 (40) | 74 (27) | |
Higher than high school | 3 (50) | 1 (3) | 14 (5) |
Data are presented as n (%) or mean ± SD. Control participants were selected with propensity score–matching sex, BMI, and pubertal status at ratio of five control participants per case patient.
Statistical comparison between group differences for case patients versus control participants.
Two-sample t test.
Fisher exact test.