Extended Data Fig. 9. Klüver Barrera staining of the RELN-COLBOS case, the APOECh case, a representative PSEN1 E280A FAD case and a representative SAD case.
Klüver-Barrera staining using luxol fast blue staining for myelin and cresyl violet staining for neuronal perikaryal in selected brain regions. Code-colored lines, regions of interest for neuronal density measurements in Cornu Ammonis (CA) structures CA1, CA2, and CA3, together with the Dentate Gyrus, Subiculum, Presubiculum and Entorhinal cortex. Scale bar, 3 mm.