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. 2023 May 19;29(5):1273–1286. doi: 10.1038/s41591-023-02324-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a, Visual representation of the associations between immune modules, immune categories, OS, PFS and the Pearson correlation between the MBR score and the immune traits. Inset highlights the significant Pearson correlations (P < 0.05), associations with FDR < 0.2 are indicated with a yellow dot. IFN, interferon; ES, enrichment score. b,c, Kaplan–Meier curves of OS by mICRoScore in AC-ICAM (b) and TCGA-COAD (c). d,e, Kaplan–Meier curve of OS in ICR-high samples by mICRoScore in AC-ICAM (d) and TCGA-COAD (e). Overall P value is calculated by log-rank test. Vertical lines indicate censor points. HRs and 95% confidence intervals are calculated by Cox proportional hazard regression. All P values are two-sided; n reflects the independent number of samples.