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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Pediatr Dermatol. 2023 Jan 3;40(3):428–433. doi: 10.1111/pde.15223

Table 3.

Initial acne therapy used within the first 6 months of the acne diagnosis, by BMI class

Type of acne therapy All acne cases (N=643) Age- and sex-specific BMI percentile class
Underweight or Normal (N=373) Overweight (N=111) Obese (N=97) P-value

At least one of the following 634 (98.6%) 367 (98.4%) 111 (100.0%) 94 (96.9%) --
 Over the counter medication 307 (47.7%) 177 (47.5%) 56 (50.5%) 47 (48.5%) 0.86
 Prescription topical medication 483 (75.1%) 276 (74.0%) 90 (81.1%) 69 (71.1%) 0.20
  Topical retinoids 365 207 72 44
  Topical antibiotics or benzoyl peroxide 277 163 45 43
  Other 14 9 0 3
 Prescription systemic medication* 53 (8.2%) 20 (5.4%) 9 (8.1%) 10 (10.3%) 0.18
  Systemic antibiotics 52 20 9 9
  Hormonal therapy or oral contraceptives 3 2 0 1
 Oral isotretinoin 2 (0.3%) 2 (0.5%) 0 (0.0%) 0 (0.0%) --
 Other^ 2 (0.3%) 1 (0.3%) 0 (0.0%) 0 (0.0%) --

Results based on the 581 acne cases with available BMI and without pre-existing relevant endocrine disorders.

The use of each type of medication was compared between the three BMI classes using the chi-square test.

*

Some patients may have used more than one type of prescription topical medication or more than one type of prescription systemic medication.

^

topical hydrocortisone [1 patient]; comedone extraction [1 patient]