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. Author manuscript; available in PMC: 2023 May 23.
Published in final edited form as: Lancet Infect Dis. 2021 Apr 14;21(8):1120–1128. doi: 10.1016/S1473-3099(21)00142-0

Figure 2: Reduced heterozygosity on the sampled loci around the pfk13 gene in R561H isolates.

Figure 2:

A total of 33 R561H mutations(nine from Masaka and 24 from Rukara) and 49 wildtype isolates (24 from Masaka and 25 Rukara) are shown (samples with mixed infections or missing data at any loci were excluded). We observed distinct haplotypes with the R561H mutation(compared with the wildtype (blue and green lines), with a reduction in the heterozygosity in those with the R561H mutation. The heterozygosity of the wildtype genotypes was significantly different and higher than the one observed in the sympatric R561H mutant haplotypes in the two populations.