Table 3. Laboratory result comparisons by neurologic symptoms in patients with babesiosis admitted to Yale-New Haven Hospital, New Haven, Connecticut, USA, January 2011–October 2021*.
| Laboratory result, median (IQR) | Reference range | Headache |
Confusion/delirium |
Impaired consciousness |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Yes, n = 52 | No, n = 111 | p value† | Yes, n = 27 | No, n = 136 | p value† | Yes, n = 24 | No, n = 139 | p value† | ||||
| Hematologic function | ||||||||||||
| Lowest hematocrit | M, 40%–52%; F, 37%–53% | 25.9 (16.2–35.6) | 26.0 (19.4–32.6) | 0.581 | 24.0 (16.5–31.5) | 26.4 (18.8–34) | 0.088 | 23.6 (15.7–31.5) | 26.4 (18.9–33.9) | 0.024 | ||
| Lowest platelet count |
150–400 × 109/L |
78.5 (4.0–153.0) |
82.0 (23.0–141.0) |
0.881 |
|
68.0 (1.0–135.0) |
82.0 (−5.0 to 230.0) |
0.339 |
|
59.5 (−5.0 to 124.0) |
84.0 (17.0–151.0) |
0.084 |
| Hepatic function | ||||||||||||
| Highest AST | 3–40 U/L | 66.0 (25.5–106.5) | 76.0 (38.0–114.0) | 0.277 | 76.0 (42.0–110.0) | 75.5 (32.5–118.5) | 0.813 | 81.0 (48.0–114.0) | 75.0 (33.0–117.0) | 0.909 | ||
| Highest ALT |
3–40 U/L |
61.0 (10.0–112.0) |
63.0 (9.0–117.0) |
0.809 |
|
54.0 (8.0–100.0) |
63.5 (12.5–114.5) |
0.568 |
|
49.0 (4.0–102.0) |
63.0 (13.0–113.0) |
0.441 |
| Renal function | ||||||||||||
| Highest BUN | 7–20 mg/dL | 17.0 (4.5–29.5) | 24.0 (5.0–43.0) |
0.002 | 31.0 (−3.0 to 65.0) |
20.0 (5.5–34.5) | 0.025 | 33.0 (0.0–66.0) |
20.0 (5.0–35.0) | 0.005 | ||
| Highest creatinine | 0.5–1.2 mg/dL | 1.00 (0.96–1.40) | 1.1 (0.3–1.9) | 0.091 | 1.5 (0.7–2.3) | 1.0 (0.5–1.5) | <0.001 | 1.5 (0.3–2.7) | 1.0 (0.5–1.5) | 0.002 | ||
| Lowest GFR | ≥60 mL/min | 76.0 (37.5–114.5) | 67.0 (21.0–113.0) | 0.007 | 46.0 (3.0–89.0) | 73.0 (33.5–112.5) | <0.001 | 47.0 (1.0–93.0) | 73.0 (33.0–113.0) | 0.003 | ||
*Boldface indicates significance. ALT, alanine transaminase; AST, aspartate transaminase; BUN, blood urea nitrogen; GFR, glomerular filtration rate; IQR, interquartile range. †By Wilcoxon 2-sample test.