Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Apr 6;3(5):100297. doi: 10.1016/j.xgen.2023.100297

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 The Author(s)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Amplification of total genetic effect in relation to testosterone levels

(A) The relationship between testosterone level bins and estimated magnitude of genetic effect on traits is shown for three traits. The magnitude of genetic effect is estimated using the slope of the regression of phenotypic values to PGSs in that bin. The units on the y axis are effect per standard deviation (SD) of the PGSs across all individuals in all bins. The hollow data points are bins with overlapping testosterone ranges between males and females; these are based on fewer individuals (∼800 compared with ∼2,200 in other bins) and not included in the regression. Figure S13 show all other traits analyzed.

(B) The correlation for each sex (90% CI) are shown for all 27 traits. Traits are ordered in descending order of male-female differences in Pearson correlation.