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. 2000 Nov;74(21):9937–9945. doi: 10.1128/jvi.74.21.9937-9945.2000

FIG. 7.

FIG. 7

Effects of modified (Morph) and unmodified (Phos) antisense DNA oligomers (oligo) on the stability of the target RNA. Viral RNAs are cleaved by the MuLV RT enzyme in the presence of unmodified DNA oligomers (lanes 3, 5, and 7) into the expected RNA products (antiPal [α Pal], 300- and 130-nt fragments; antiG5 [α G5], 210- and 220-nt fragments; antiCon1 [α Con1], 200- and 240-nt fragments). Viral RNAs are not altered in the presence of modified oligonucleotides (lanes 4, 6, and 8). The presence (+) or absence (−) of the RT enzyme is indicated over the gel.