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. 2023 May 22;14:2937. doi: 10.1038/s41467-023-38539-w

Fig. 6. REST could directly improve the interpretation of nucleosome in vivo.

Fig. 6

A Tomographic slice of frog erythrocyte nuclei thinned by cryo-FIB. B 3D REST-restored view of the tomographic data in A. Yellow circle labelled the particle displayed in C. C The densities of nucleosome which were directly extracted from REST-restored tomogram. D The different conformation of subtomogram averaged map calculated from the same sample. Nucleosomes without (pink) or with linker DNA (cyan), and other non-classic nucleosome-like densities (grey) are coloured differently in BD.