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. 2023 Apr 20;3(5):100303. doi: 10.1016/j.xgen.2023.100303

Figure 4.

Figure 4

exRBPs associate with specific vesicular and non-vesicular exRNA carriers

(A) Enrichment of exRBP-specific exRNA cargo within specific vesicular and non-vesicular carrier cargo types (CTs).

(B) Upset plot depicting the number of RBPs that show consistent enrichment for specific CTs by multiple methods.

(C) Enrichments for specific exRBP biotype cargo by CT tested by Kruskal-Wallis test. Whiskers extend to min and max, and outliers are greater than 1.5 interquartile range (IQR). ∗p < 0.05.

(D) Distributions of exRBPs p values of coefficient of variance tests across loci vs. permuted locus coefficient of variance.

(E) Computational assignment of candidate RBC exRBPs to CT1 and CT4 CTs.