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. Author manuscript; available in PMC: 2023 Jul 8.
Published in final edited form as: Circ Res. 2022 Jun 6;131(2):e51–e69. doi: 10.1161/CIRCRESAHA.122.320991

Figure 1.

Figure 1.

Protein-protein interaction network of differentially methylated positions associated with CVD and with arsenic in the Strong Heart Study. Arsenic-associated and CVD-associated DMPs were annotated to the nearest protein coding gene and included in a protein-protein interaction network. The interactions between nodes were obtained using STRING database v11.0,60 selecting all active interaction sources with a confidence score of 0.4. The network was analyzed and displayed using edge weighted spring embedded layout with Cytoscape v3.8.2.61.