TABLE 4.

The perinatal outcomes in fetuses with microcephaly.

		Syndromic microcephaly vs. primary microcephaly			ES testing results
Perinatal outcomes	Total (n = 224)	Primary microcephaly (n = 38)	Syndromic microcephaly (n = 186)	p-value	CSVs (n = 31)	VUS (n = 30)	Negative (n = 101)	p-value
TOP	91(40.63%)	25(65.78%)	66(35.48%)	0.000	21(67.74%)	15(50.00%)	31(30.69%)	0.001
Live birth	129(57.60%)	12(31.56%)	117(62.90%)	0.000	10(32.26%)	14(46.67%)	67(66.34%)	0.001
Intrauterine death	4(1.78%)	1(5.26%)	3(1.61%)	0.520	0	1(3.33%)	3(2.97%)	0.652

CSVs, clinically significant variants; VUS, variants of unknown significance; TOP, termination of pregnancy.