Table 1.
Characteristic | Number |
---|---|
Age (mean, standard deviation, in years), range | 65.8 +/- 8.3, 44-82 |
Race | |
Black White Asian More than one |
33 (49.2%) 32 (47.8%) 1 (1.5%) 1 (1.5%) |
Ethnicity | |
Hispanic Non-Hispanic |
15 (22.4%) 52 (77.6%) |
Treatment | |
Surgery | 52 (78%) |
TAH
“ + BSO “ + BSO + PLND “ + BSO + PLND + Omentectomy and debulking |
2
2 10 38 |
Initial chemotherapy | 65 (97%) |
Carboplatin
“ + Paclitaxel “ + Paclitaxel + Bevacizumab “ + Paclitaxel + Herceptin “ + Paclitaxel + Pembrolizumab “ + Taxotere “ + Taxotere + Bevacizumab |
2
55 4 1 1 1 1 |
Radiation therapy | 23 (34.3%) |
FIGO Stage at diagnosis | |
I II III IV |
13 (19.4%) 3 (4.5%) 18 (26.9%) 33 (49.2%) |
Metastatic disease | 33 (49.2%) |
Recurrent disease | 27 (40.3%) |
Mutational status | |
TP53
PIK3CA FBXW7 ARID1A PTEN BRCA1 BRCA2 CTNNB1 ERBB2 alterations AKT1,2,3 KRAS |
55/58 (94.8%) 14/61 (22.9%) 10/60 (15%) 3/32 (9.4%) 5/57 (8.7%) 2/57 (3.5%) 2/57 (3.5%) 1/58 (1.7%) 12/37 (32.4%) 2/61 (3.3%) 1/61 (1.6%) |
Immunohistochemistry | |
ER PR PTEN TOP2A TOP01 RRM1 MGMT TS TUBB3 |
43/65 (66.2%) 24/65 (36.9%) 51/56 (91.1%) 20/22 (90.9%) 14/22 (63.6%) 4/20 (20%) 3/5 (60%) 10/22 (45.5%) 11/22 (50%) |
TAH, total hysterectomy; BSO, Bilateral salpingoophorectomy; PLND, pelvic lymph node dissection.