FIG. 5.
In vitro stimulation with either Lm-gag (a) or Lmdaldat-gag (b) enhances the response to the immunodominant peptide (gag29) that is recognized in vivo. Cell lines were analyzed 15 days after in vitro vaccination by a 4-h 51Cr release assay against autologous B-LCL target cells incubated with 20-mer overlapping peptides encoded by HXB.2 p24Gag gene (21). The experiment was performed at an E:T ratio of 20:1.