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Table 1. Classification of heart failure based on LVEF.

Type of HF HFrEF HFpEF HFnEF
HFsrEF HFmrEF
CRITERIA
 1 Symptoms ± signs Symptoms ± signs Symptoms ± signs Symptoms ± signs
 2 LVEF ≤ 40% LVEF 41-49% LVEF 50-59% LVEF ≥ 60%
 3 Objective evidence of cardiac structural and functional abnormalities consistent with spontaneous or provokable increased LV filling pressures; and elevated natriuretic peptides* Objective evidence of cardiac structural and functional abnormalities consistent with spontaneous or provokable increased LV filling pressures; and elevated natriuretic peptides*

HF, heart failure; HfmrEF, heart failure with mildly reduced ejection fraction; HfnEF, heart failure with normal ejection fraction; HfpEF, heart failure with preserved ejection fraction; HFrEF, heart failure with reduced ejection fraction; HfsrEF, heart failure with severely reduced ejection fraction; LV, left ventricular; LVEF, left ventricular ejection fraction.

* B-type natriuretic peptide ≥ 35 pg/mL and/or N-terminal pro-B type natriuretic peptide ≥ 125 pg/mL.