Fig. 5.

OPUS visualization of HIFU lesion progression in a not fixed ex vivo liver specimen. (a) OA images before (Pre), during (HIFU) and after (Post) HIFU ablation. Scalebar – 3 mm. (b) Corresponding US images before (Pre), during (HIFU) and after (Post) HIFU ablation. Scalebar – 3 mm. Yellow dashed lines delineate the tissue boundary. (c) Time-lapse OA and US readings in the region-of-interest (ROI) indicated with blue squares in (a) and (b). Dark blue curves show the signals after applying a moving average filter with a window size of 30 while the raw (unfiltered) signals are shown in the background. The vertical black dashed lines indicate time points before (Pre), during (HIFU) and after (Post) HIFU exposure. (d) Tissue displacements calculated using the surface OA and US signal intensities in the blue ROIs (a) and (b).