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Prediction performance of the microRNA signature in the validation set.
| AUC (95% CI) |
Sensitivity (95% CI) |
Specificity (95% CI) |
PPV (95% CI) |
NPV (95% CI) |
Accuracy (95% CI) |
Cut-off point | p value | |
|---|---|---|---|---|---|---|---|---|
| Three-microRNA signature | 0.77 (0.70 to 0.84) |
0.99 (0.95 to 1.00) |
0.26 (0.17 to 0.38) |
0.63 (0.60 to 0.67) |
0.95 (0.73 to 0.99) |
0.67 (0.60 to 0.74) |
0.65 | < 0.001 |
AUC, area under the curve; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value.
