Table 2. First Chronic Obstructive Pulmonary Disease Exacerbation and Pneumonia Hospitalization in Patients Using LAMA-LABAs vs ICS-LABAs in the Propensity Score–Matched Cohort.
Event | ICS-LABA–associated events per 1000 PY | LAMA-LABA–associated events per 1000 PY | HR (95% CI) |
---|---|---|---|
Moderate or severe COPD exacerbation | 363.6 | 320.6 | 0.92 (0.89-0.96) |
Moderate COPD exacerbation | 321.5 | 286.6 | 0.93 (0.90-0.97) |
Severe COPD exacerbation | 47.3 | 39.8 | 0.85 (0.77-0.94) |
Pneumonia hospitalization | 104.0 | 82.1 | 0.80 (0.75-0.86) |
Abbreviations: COPD, chronic obstructive pulmonary disease; HR, hazard ratio; ICS, inhaled corticosteroid; LABA, long-acting β-agonist; LAMA, long-acting muscarinic antagonist; PY, person-years.