TABLE 3.

Coentry of HCV and α-sarcin is specific for low-density particles^a

Infection conditions	Protein synthesis (cpm)b in:
	MOLT-4	L cells
Mock (1.08 g/ml)	24,541	19,442
Mock (1.16 g/ml)	22,616	NTd
HCV (1.08 g/ml)	3,020c	23,855
HCV (1.16 g/ml)	18,650	17,588
No α-sarcin	22,371	22,760

^aCells were incubated with low-density (1.08 g/ml) or intermediate-density (1.16 g/ml) fractions from HCV- or mock-infected plasma in the presence or absence of α-sarcin. Cellular protein synthesis was determined 1 h postincubation by labeling with [³⁵S]methionine as described in Materials and Methods. 

^bData represent [³⁵S]methionine incorporation. 

^cHCV cpm values (1.08 g/ml) were significantly different from Mock (1.08 and 1.16 g/ml), HCV (1.16 g/ml), and no a-sarcin (P < 0.001; paired t test). 

^dNT, not tested.