Table 3.
Time course of psychiatric patients cohorts with neural autoantibodies.
| Parameter | A Cohort with Dementia (n = 14) |
B Cohort with MCI (n = 7) |
C Cohort with Psychotic Disorders (n = 6) |
|---|---|---|---|
| Immunotherapy | 5/14 (36%) |
2/7 (29%) |
5/6 (83%) |
| Steroids | 4/14 (29%) |
2/7 (29%) |
3/6 (50%) |
| IVIGs | 0/14 + (0%) |
0/7 (0%) |
3/6 + (50%) |
| Rituximab | 0/14 (0%) |
0/7 (0%) |
1/6 (17%) |
| Affective Symptoms | |||
| Improvement | 1/14 (7.1%) |
1/7 (14%) |
0/6 (0%) |
| Deterioration | 1/14 (7.1%) |
2/7 (29%) |
1/6 (17%) |
| Stable | 1/14 (7.1%) |
2/7 (29%) |
0/6 (0%) |
| Psychotic Symptoms | |||
| Improvement | 1/14 (7.1%) |
1/7 (14%) |
5/6 (83%) |
| Deterioration | 0/14 (0%) |
0/7 (0%) |
0/6 (0%) |
| Stable | 0/14 (0%) |
0/7 (0%) |
1/6 (17%) |
| Cognitive Dysfunction | |||
| Improvement | 2/14 (14%) |
1/7 (14%) |
0/6 (0%) |
| Deterioration | 6/14 (43%) |
4/7 (57%) |
1/6 (17%) |
| Stable | 6/14 (43%) |
1/7 (14%) |
4/6 (67%) |
Abbreviation: IVIG = intravenous immunoglobulins, MCI = mild cognitive impairment. Fisher´s exact test was performed between the three groups: A vs. C, + p < 0.05.