Table 5. Absolute difference in cross-sectional area (CSA) measurements (mm2) between tunnel nerves and those proximal to the tunnel points on the same side by high-resolution ultrasonography in healthy volunteers and leprosy household contacts.
Nerves | Healthy volunteers | Seropositive HC | Seronegative HC | p1 value | p2 value | p3 value | |
---|---|---|---|---|---|---|---|
Median (ΔMtpt) | n | 106 | 90 | 57 | |||
Mean ± SD | 1.71 ± 1.25 | 1.61 ± 1.04 | 1.40 ± 0.82 | >0.9999 | >0.9999 | >0.9999 | |
Median (Q1/Q3) | 1 (1/2) | 2 (1/2) | 2 (1/2) | ||||
95% CI | [1.47–1.95] | [1.4–1.85] | [1.25–1.66] | ||||
Abnormal (>5.46) | 0 | 0 | 0 | ||||
Ulnar (ΔUtpt) | n | 106 | 98 | 60 | |||
Mean ± SD | 1.09 ± 0.88 | 1.07 ± 0.91 | 0.98 ± 0.72 | >0.9999 | >0.9999 | 0.7345 | |
Median (Q1/Q3) | 1 (0/2) | 1 (0/2) | 1 (0,25/1) | ||||
95% CI | [0.93–1.26] | [0.89–1.25] | [0.79–1.17] | ||||
Abnormal (>3.73) | 0 | 1 (1.0%) | 0 | ||||
Tibial (ΔTtpt) | n | 106 | 98 | 60 | |||
Mean ± SD | 0.8 ± 0.60 | 0.60 ± 0.71 | 0.47 ± 0.60 | >0.9999 | 0.8095 | 0.8005 | |
Median (Q1/Q3) | 1 (0/1) | 0 (0/1) | 0 (0/1) | ||||
95% CI | [0.47–0.7] | [0.46–0.76] | [0.31–0.62] | ||||
Abnormal (>2.38) | 0 | 0 | 0 |
HC = household contacts; n = number of nerves; SD = standard deviation; Q1 = 25th percentile; Q3 = 75th percentile; 95% CI– 95% confidence interval; p1 value = healthy volunteers vs. seropositive HC; p2 value = healthy volunteers vs. seronegative HC; p3 value = seropositive HC vs. seronegative HC.
*Statistically significant.