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. 2023 May 16;2023:3990035. doi: 10.1155/2023/3990035

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Copyright © 2023 Guo-Wei Zong et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Two examples of the local explanation of the predictions using the Shapley Additive exPlanation (SHAP) values. (a) Predicted type 2 diabetes patient without diabetic retinopathy. (b) Predicted type 2 diabetes patient with diabetic retinopathy. Factors that push the predicted score higher compared to the base value (mean prediction) are coloured red, and those pushing lower the prediction are shown in blue. C18 : 1OH: 3-hydroxy-octadecylcarnitine; T2D: type 2 diabetes; SBP: systolic blood pressure; Glu: glutamate; C18 : 1: octacarbonylcarnitine; Phe: phenylalanine; C18 : 2: octadecadienylcarnitine.