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. 2023 May 16;22:100508. doi: 10.1016/j.lana.2023.100508

Table 3.

Correlates of behavioral transitions in ENDS use over Waves 3–5, PATH Study.

Characteristics ENDS use transitions
Initiation (n = 12,856)
Relapse (n = 14,210)
Progression (n = 3044)
Cessation (n = 4492)
Crude n/number at risk (Wt%) Adjusted OR Crude n/number at risk (Wt%) Adjusted OR Crude n/number at risk (Wt%) Adjusted OR Crude n/number at risk (Wt%) Adjusted OR
Overall 964 (1.7) 1694 (12.1) 356 (13.0) 1939 (46.3)
Age group
 18–24a 490 (7.6) Ref 736 (17.0) Ref 168 (15.2) Ref 788 (46.6) Ref
 25–44 283 (2.1) 0.25 (0.19–0.32) 714 (11.9) 0.56 (0.46–0.69) 127 (12.4) 0.89 (0.54–1.46) 703 (48.6) 0.87 (0.63–1.20)
 45–64 161 (1.2) 0.14 (0.10–0.19) 215 (8.2) 0.38 (0.28–0.51) 52 (10.3) 0.60 (0.35–1.04) 383 (43.8) 0.76 (0.52–1.11)
 65+ 30 (0.3) 0.04 (0.03–0.07) 29 (7.0) 0.39 (0.23–0.66) 11 (16.8) 0.70 (0.29–1.69) 65 (44.2) 1.06 (0.56–2.02)
Sex
 Femalea 469 (1.5) Ref 848 (11.7) Ref 150 (11.7) Ref 975 (48.1) Ref
 Male 494 (2.0) 1.18 (0.93–1.51) 846 (12.3) 0.88 (0.73–1.06) 206 (14.0) 1.16 (0.79–1.70) 964 (44.9) 0.95 (0.72–1.25)
Sexual Orientation
 Straighta 854 (1.7) Ref 1418 (11.5) Ref 295 (12.7) Ref 1661 (46.6) Ref
 LGB 108 (4.3) 1.28 (0.82–2.00) 260 (16.7) 1.18 (0.91–1.53) 59 (14.0) 1.15 (0.64–2.06) 267 (44.9) 0.91 (0.61–1.38)
 Not reported 2 (0.1) 0.14 (0.02–0.97) 16 (13.8) 1.48 (0.69–3.18) 2 (14.3) 2.88 (0.42–19.53) 11 (31.3) 1.37 (0.27–7.06)
Race/ethnicity
 Non-Hispanic White 484 (1.5) Ref 1040 (12.4) Ref 240 (14.4) Ref 1182 (44.0) Ref
 Non-Hispanic Black 182 (2.4) 1.29 (0.95–1.75) 180 (10.4) 0.97 (0.71–1.34) 37 (12.0) 0.93 (0.48–1.77) 244 (53.4) 0.88 (0.53–1.45)
 Hispanic 219 (2.5) 1.44 (1.07–1.95) 310 (11.1) 1.07 (0.84–1.36) 48 (7.5) 0.29 (0.16–0.54) 372 (55.6) 1.29 (0.86–1.93)
 Other races 79 (1.4) 0.66 (0.46–0.94) 164 (13.9) 1.23 (0.91–1.68) 31 (12.9) 0.71 (0.32–1.57) 141 (42.5) 0.88 (0.52–1.51)
Educational
 Less than high school 166 (2.0) Ref 322 (12.1) Ref 67 (9.3) Ref 452 (51.7) Ref
 High school graduate 260 (1.9) 0.95 (0.67–1.34) 421 (12.7) 1.06 (0.80–1.41) 92 (13.0) 1.68 (0.90–3.12) 483 (45.7) 1.16 (0.78–1.74)
 Some college 387 (2.2) 1.10 (0.80–1.53) 735 (13.0) 1.21 (0.95–1.55) 150 (13.5) 1.42 (0.81–2.48) 789 (45.2) 1.16 (0.82–1.65)
 Bachelor’s degree or more 150 (1.1) 0.73 (0.48–1.12) 212 (9.3) 1.03 (0.75–1.41) 46 (16.5) 2.33 (1.22–4.46) 203 (43.6) 0.91 (0.56–1.47)
Income
 Less than $25,000a 357 (2.3) Ref 662 (13.1) Ref 132 (11.3) Ref 854 (50.8) Ref
 $25,000–$49,999 206 (1.9) 1.18 (0.89–1.57) 410 (12.1) 1.01 (0.81–1.26) 84 (13.1) 0.72 (0.42–1.24) 439 (44.3) 0.85 (0.60–1.19)
 $50,000–$99,999 190 (1.5) 1.07 (0.77–1.48) 346 (11.2) 0.95 (0.73–1.23) 86 (15.5) 0.92 (0.55–1.54) 369 (44.4) 0.88 (0.63–1.22)
 $100,000 or more 154 (1.5) 1.24 (0.84–1.83) 200 (11.0) 0.96 (0.72–1.29) 37 (14.3) 0.72 (0.38–1.39) 179 (39.6) 0.70 (0.46–1.07)
 Not reported 57 (1.2) 1.00 (0.58–1.73) 76 (12.5) 0.79 (0.52–1.19) 17 (11.6) 0.63 (0.20–1.98) 98 (48.0) 0.68 (0.36–1.28)
Internalizing symptoms
 No 561 (1.3) Ref 818 (10.1) Ref 177 (11.8) Ref 1043 (46.5) Ref
 Yes 403 (3.3) 1.78 (1.39–2.29) 874 (14.8) 1.30 (1.09–1.56) 178 (14.1) 1.13 (0.76–1.68) 890 (46.2) 1.11 (0.85–1.47)
Externalizing symptoms
 No 900 (1.7) Ref 1511 (11.6) Ref 319 (12.8) Ref 1781 (46.1) Ref
 Yes 64 (5.5) 1.18 (0.75–1.85) 181 (18.8) 1.32 (0.99–1.74) 36 (14.3) 1.16 (0.62–2.18) 151 (48.9) 1.59 (0.96–2.63)
Current use of cigarettes
 No 722 (1.4) Ref 672 (9.1) Ref 133 (14.1) Ref 759 (40.1) Ref
 Yes 242 (6.6) 5.57 (4.15–7.48) 1021 (15.0) 2.34 (1.88–2.92) 222 (12.3) 0.86 (0.54–1.37) 1180 (51.3) 1.55 (1.18–2.02)
Current other tobacco use
 No 865 (1.6) Ref 1365 (11.3) Ref 281 (13.9) Ref 1449 (44.8) Ref
 Yes 99 (5.1) 2.53 (1.76–3.66) 329 (17.4) 1.49 (1.17–1.89) 75 (9.7) 0.63 (0.37–1.06) 490 (52.2) 1.16 (0.80–1.68)
Past 12-month cannabis useb
 No 618 (1.3) Ref 802 (9.4) Ref 174 (12.8) Ref 1007 (45.1) Ref
 Yes 161 (6.1) 2.99 (2.22–4.02) 288 (12.9) 1.31 (1.06–1.61) 52 (14.3) 1.12 (0.72–1.74) 269 (43.1) 0.81 (0.59–1.11)
Nicotine harm perception
 None or little harm 218 (3.5) Ref 582 (13.8) Ref 172 (14.9) Ref 816 (38.3) Ref
 Very harmful 741 (1.5) 0.79 (0.60–1.05) 1106 (11.3) 0.99 (0.82–1.19) 183 (11.5) 0.75 (0.51–1.09) 1111 (54.4) 1.50 (1.15–1.97)
ENDS absolute harm perception
 None or little harm 431 (2.6) Ref 1033 (13.8) Ref 291 (13.8) Ref 1436 (43.3) Ref
 Very harmful 521 (1.4) 0.86 (0.67–1.10) 641 (10.1) 0.75 (0.63–0.90) 62 (9.7) 0.74 (0.42–1.32) 474 (60.3) 1.32 (0.91–1.93)
Comparative harm perception
 Less harmful 246 (2.3) Ref 577 (13.8) Ref 205 (16.3) Ref 905 (38.9) Ref
 Equally or more harmful 703 (1.6) 0.91 (0.69–1.19) 1098 (11.3) 0.75 (0.63–0.90) 148 (9.7) 0.66 (0.43–1.02) 1016 (56.9) 1.31 (0.98–1.75)
ENDS nicotine dependencec 16.7 (1.6)c 1.03 (1.02–1.04) 13.9 (0.7)c 0.97 (0.96–0.98)

W = wave, Wt% = weighted percentage, CI = confidence interval, LGB = Lesbian, Gay, bisexual, or something else, ENDS = electronic nicotine delivery system, Ref = reference.

All analyses were weighted using PATH Wave 5 all-wave weights. Bold-faced indicates p < 0.05.

a

Unweighted n and weighted row percentages.

b

Missing for cannabis use was >5% within transition outcomes.

c

Nicotine dependence shows the weighted mean and standard error among individuals who progressed or discontinued using ENDS.