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. 2023 Apr 6;22(5):100544. doi: 10.1016/j.mcpro.2023.100544

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© 2023 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 8 — Basal state transcriptome versus proteome integration.A, Venn diagram showing the number of overlapping proteins in the supraoptic nucleus (SON) and neurointermediate lobe (NIL) and genes in the SON in control conditions. B, schematic representation of the gene and protein dynamics in the SON and NIL in control conditions according to comparisons from the Venn diagram. Generated using BioRender (https://biorender.com/). C, regulatory peptides detected in the SON without or very low transcripts in this structure. D, D', immunohistochemistry against HCRT in the SON of control and water-deprived (WD) rats. E, E', immunohistochemistry against NPY in the SON of control and WD rats. F, F', immunohistochemistry against AGRP in the SON of control and WD rats. Images are representative of n = 4. Scale bar represents 25 μm. NPY, neuropeptide Y.