Figure 1.

Study cohort and summary of findings. The top box shows the number of persons enrolled and the person-years of follow-up for the CAB arm of HPTN 083. The second box shows the number of HIV infections identified in the blinded phase of the study and the annual incidence of HIV infection in the CAB arm [1]. The third box shows the number of participants evaluated in this report. The fourth box shows how many participants had major INSTI RAMs detected at any study visit, among the 16 CAB cases analyzed to date; this box also shows the breakdown of cases by case type (baseline, oral phase, injection phase). The lower row of boxes shows the number of cases and break down of cases by case type with major INSTI RAMs at the first visit where the site detected infection based on results from HIV rapid tests and an instrumented HIV antigen/antibody test (first site positive visit) and at the first HIV positive visit. Abbreviations: Ab, antibody; Ag, antigen; c/mL, copies per mL; CAB, cabotegravir; HIV, human immunodeficiency virus; INSTI, integrase strand transfer inhibitor; RAM, resistance-associated mutation; VL, viral load.