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. 2023 May 23;13:8342. doi: 10.1038/s41598-023-33743-6

Table 5.

Multivariate-adjusted OR of TC increase or non-decrease after T2D diagnosis among users of lipid-lowering drugs.

Among users of lipid-lowering drugs
Low–middle or low–high vs. low–low (ref.) Middle–middle or middle–high vs. middle–low (ref.) high–high vs high–middle or high–low (ref.)
Age, years
 < 60 1.00 (ref.) 1.00 (ref.) 1.00 (ref.)
 ≥ 60 0.76 (0.61–0.95) 0.93 (0.83–1.05) 0.98 (0.83–1.16)
Sex
 Men 1.00 (ref.) 1.00 (ref.) 1.00 (ref.)
 Women 1.88 (1.44–2.46) 1.43 (1.24–1.65) 1.32 (1.08–1.60)
Socioeconomic status
 1st quartile (lowest) 1.05 (0.75–1.46) 1.08 (0.90–1.29) 1.28 (1.01–1.64)
 2nd quartile 1.01 (0.74–1.37) 1.11 (0.94–1.29) 1.16 (0.93–1.45)
 3rd quartile 0.88 (0.67–1.15) 1.02 (0.89–1.18) 1.25 (1.02–1.52)
 4th quartile (highest) 1.00 (ref.) 1.00 (ref.) 1.00 (ref.)
BMI, kg/m2
 < 25 1.00 (ref.) 1.00 (ref.) 1.00 (ref.)
 ≥ 25 1.02 (0.83–1.28) 0.90 (0.80–1.01) 0.98 (0.83–1.15)
Smoking status
 Non-smoker 1.00 (ref.) 1.00 (ref.) 1.00 (ref.)
 Smoker 1.38 (1.02–1.88) 0.99 (0.84–1.15) 1.34 (1.07–1.68)
Physical activity, per week
 None 1.34 (0.86–2.10) 1.19 (0.94–1.51) 1.50 (1.08–2.09)
 1–2 1.21 (0.75–1.94) 1.11 (0.86–1.43) 1.35 (0.95–1.92)
 3–4 0.81 (0.49–1.35) 0.99 (0.76–1.30) 1.46(1.00–2.13)
 5–6 0.74 (0.40–1.39) 0.77 (0.56–1.05) 0.92 (0.81–1.19)
 7 1.00 (ref.) 1.00 (ref.) 1.00 (ref.)
Alcohol consumption, per week
 No 1.00 (ref.) 1.00 (ref.) 1.00 (ref.)
 Yes 1.34 (1.03–1.75) 0.92 (0.80–1.05) 0.98 (0.81–1.19)
Systolic blood pressure, mmHg
 < 120 1.00 (ref.) 1.00 (ref.) 1.00 (ref.)
 120–129.9 1.15 (0.83–1.59) 1.09 (0.92–1.13) 0.81 (0.64–1.02)
 ≥ 130 1.53 (1.16–2.01) 1.23 (1.07–1.42) 1.20 (0.99–1.47)
Fasting serum glucose, mg/dL
 < 100 1.00 (ref.) 1.00 (ref.) 1.00 (ref.)
 100–125.9 1.11 (0.83–1.49) 1.14 (0.98–1.33) 1.39 (1.10–1.76)
 ≥ 126 1.46 (1.08–2.00) 1.70 (1.45–1.99) 2.00 (1.59–2.52)

TC total cholesterol, OR odds ratio.