Figure 4.
Effect of M(27–39)-HTPP on the expression of apoptosis-related genes and proteins in HepG2 cells
(A) Relative mRNA expression of P53, Bcl-2, Bax, Caspase-9, Caspase-3 and PARP in HepG2 cells.
(B) Western blot and relative protein expression of P53, Bcl-2, Bax, Cyt-C, Cleaved Caspase-9, Cleaved Caspase-3 and Cleaved PARP in HepG2 cells. ∗p< 0.05; ∗∗p< 0.01; ∗∗∗p< 0.001. As compared with the negative control group. #p< 0.05; ##p< 0.01; ###p< 0.001. ▲p< 0.05; ▲▲p< 0.01; ▲▲▲p< 0.001. N.S., not significant. Data are presented as the mean ± SD.