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. 2022 Dec 31;315(5):1355–1365. doi: 10.1007/s00403-022-02508-y

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Fig. 2 — p53 protein and gene expression before and after isotretinoin therapy. a Illustrates the changes of p53 protein and b the changes of p53 gene expression of back skin biopsies of acne patients before and after 6 weeks of oral isotretinoin treatment compared to acne-free control skin biopsies