Figure 5.

Chronic herpes simplex virus (HSV) 2 infection is associated with an increase in breadth of antigenic targets. Western blots were performed with HSV-2–infected or HSV-2–uninfected Vero cell lysates as the antigen and probed with pooled immune serum (n = 3) from glycoprotein D (gD)/ASO4 vaccinated and acutely or chronically HSV-2–infected (human immunodeficiency virus [HIV]–negative [HIV⁻] and HIV-positive [HIV⁺]) women. Molecular weight markers are indicated on the left, and arrows denote gD (55 KDa), glycoprotein C (gC; 78 KDa) and glycoprotein B (gB; 116 KDa).