Skip to main content
. 2023 May 23;13:172. doi: 10.1038/s41398-023-02477-4

Fig. 3. Plasma concentrations of N,N-dimethyltryptamine (DMT), DMT-N-oxide (DMT-NO), and indole-3-acetic acid (IAA) over time.

Fig. 3

Both bolus doses (15 and 25 mg) produced peak DMT levels 2 min after administration. Plasma DMT concentrations then rapidly decreased until reaching a plateau after 20 min. In the infusion-only conditions (0.6 and 1 mg/min), DMT concentrations increased until reaching a plateau at 70–80 min. After stopping the infusion at 90 min, DMT levels very rapidly decreased within 15–20 min in all conditions. The corresponding pharmacokinetic parameters are shown in Table 2 and Supplementary Table S4. Individual concentrations are shown in Supplementary Fig. S3–5.