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. 2023 May 4;26(6):106810. doi: 10.1016/j.isci.2023.106810

Figure 3.

Figure 3

Peyer’s patch germinal center deficits persist for at least 7 weeks after antibiotic exposure

(A–D) Mice were euthanized at P60, IgA was quantitated in ileal tissue (A), and Peyer’s patches were evaluated using flow cytometry. Plots show absolute abundance of (B) live CD45+ cells and (C) B cells, (D) frequency of B cells.

(E–G) Representative flow cytometry plots for Peyer’s patch GC B cell populations and summary plots for GC B cell (F) counts and (G) proportions. All data shown are from a single representative experiment of two independent experiments; plots show the mean value ±SEM; ∗ indicates p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.