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MITF inhibitor ML329 reduces CD34+ derived hMCS degranulation. CD34+ derived hMCs from three different healthy donors were assessed. KIT, FcϵRI, and MRGPRX2 were checked by flow cytometry. Degranulation was determined by flow cytometry using CD63 staining in unstimulated and ML329-treated cells (after 5 days) in the live population (propidium iodide negative staining).
