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. 2023 May 10;11:1168330. doi: 10.3389/fbioe.2023.1168330

FIGURE 1.

FIGURE 1

Schematic representation of the therapeutic cell device and its implementation in a mouse model of wound healing. The cell device is prepared by encapsulating the desired combination of engineered stable cell lines, each expressing a single soluble factor into a semipermeable container. A cell device is implanted at the site of injury, where it enhances regeneration processes by local secretion of a combination of growth factors defined by the selected engineered cells.