Table 5.
Commercially available cosmetic peptides and their bioactivity (Errante et al. 2020) [Copyright
© 2020 Errante, Ledwoń, Latajka, Rovero and Papini. Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/)]:
| Peptide name | Peptide sequence | Trade name | Bioactivity |
|---|---|---|---|
| Pentapeptide-3 | H-GPRPA-NH2 | Vialox | ACh receptor antagonist, disabling nerves’ function |
| Pentapeptide-18 | H-YAGFL-OH | Leuphasyl® | ACh decreased secretion in synaptic clefts |
| Acetyl octapeptide 1/-3 | Ac-EEMQRRAD-NH2 | SNAP-8™ | SNAP-8 competitive inhibitor, blocking SNARE complex formation |
| Palmitoyl hexapeptide-12 | Pal-VGVAPG-OH | Biopeptide EL™ | Matrix metalloproteases activity up-regulator, elastin down-regulator and collagen synthesis stimulator |
| Palmitoyl pentapeptide-4 | Pal-KTTKS-OH | Matrixyl® | Extracellular matrix proteins synthesis feedback modulator |
| Palmitoyl tripeptide-1 | Pal-GHK-OH | Biopeptide CL™ | Collagen and glycosaminoglycan synthesis stimulator |
| Palmitoyl tripeptide-5 | Pal-KVK-OH | Syn®-Coll | Transforming growth factor β stimulator inducing collagen synthesis |
| Tripeptide-10 citrulline | H-PVAPFP-OH | Decorinyl® | Collagen fibres diameter regulator, increasing endogenous collagen quality, without affecting its synthesis |
| SA1-III | Ac-MGKVVNPTQK-NH2 | KP1 | Collagen turnover modulator by protease inhibition |