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Full-length Env clones generated from the 89.6PI quasispecies
| Coreceptor use patterna | No. of clones | % of all clones | % of functional clones |
|---|---|---|---|
| CCR5 and CXCR4 (R5X4) | 30 | 60 | 86 |
| CCR5 (R5) | 4 | 8 | 11 |
| CXCR4 (X4) | 1 | 2 | 3 |
| Nonfunctional | 15 | 30 |
Coreceptor use was based on cell-cell fusion and, for selected Env clones, was confirmed by pseudotype infections.
