Fig. 1.

Single-cell landscape of 15 pancreatic adenocarcinoma samples without pre-resection treatment. (A) PDAC cell states various from patients. (B) Integrating and reclustering of PDAC cells suggested 7 major clusters. (C) UMAP plot showing tumor cell components, grouped by sample. (D) Stacked bar plot showing tumor cell components, grouped by sample. (E) Expression of marker genes of each major cluster, showed by dot plot. (F) Expression of marker gene modules and genes showed by feature plot.