Table 3.
Adjusted Associations Between Individual- and Area-Level Characteristics and Distant-Stage Lung Cancer Diagnosis Among Patients With Incident Lung Cancer in the Southern Community Cohort Study, Primary Analysis of Imputed Baseline Data, 2002 through 2019 (N = 1,572)
| Characteristic | ORa | 95% CI | P Value |
|---|---|---|---|
| Main effects | |||
| Black/African American race (reference: White) | 0.49 | 0.08-3.04 | .441 |
| Age at diagnosis | 0.98 | 0.96-1.00 | .060 |
| Male sex (reference: female sex) | 1.32 | 0.91-1.93 | .145 |
| Education (reference: less than high school) | |||
| High school | 1.23 | 0.97-1.58 | .090 |
| More than high school | 1.28 | 0.97-1.68 | .084 |
| Household income ≥ $15,000 (reference: < $15,000) | 0.92 | 0.72-1.17 | .493 |
| Marital status (reference: married) | |||
| Separated or divorced | 0.94 | 0.62-1.42 | .780 |
| Widowed | 1.53 | 0.88-2.65 | .132 |
| Single | 1.08 | 0.57-2.06 | .811 |
| Health insurance coverage (reference: no coverage) | 0.81 | 0.64-1.02 | .068 |
| Pack-years smoked | 1.00 | 1.00-1.00 | .801 |
| History of COPD (reference: no history) | 0.72 | 0.53-0.98 | .040 |
| Prior cancer diagnosis (reference: no diagnosis) | 0.98 | 0.69-1.40 | .930 |
| Charlson comorbidity index score (reference: 1) | |||
| 2 | 1.46 | 0.73-2.97 | .290 |
| 3 | 1.70 | 0.84-3.49 | .145 |
| 4 | 1.91 | 0.94-3.94 | .076 |
| 5 | 2.11 | 0.98-4.61 | .059 |
| ≥ 6 | 1.31 | 0.58-2.98 | .521 |
| Underwent colonoscopy (reference: never underwent) | 0.93 | 0.73-1.19 | .576 |
| Area deprivation (reference: quartile 1, least deprived) | |||
| Quartile 2 | 1.29 | 0.87-1.91 | .207 |
| Quartile 3 | 0.82 | 0.48-1.38 | .464 |
| Quartile 4 (most deprived) | 2.14 | 1.00-4.68 | .051 |
| Distance from comprehensive cancer center, 100-mile increments | 1.08 | 0.95-1.23 | .224 |
| Interaction effectsb | |||
| Black/African American × age at diagnosis | 1.02 | 0.99-1.05 | .193 |
| Black/African American × male sex | 0.98 | 0.62-1.54 | .925 |
| Black/African American × separated or divorced | 1.23 | 0.73-2.07 | .430 |
| Black/African American × widowed | 0.86 | 0.42-1.76 | .682 |
| Black/African American × single | 1.39 | 0.67-2.91 | .377 |
| Black/African American × area deprivation quartile 2 | 1.00 | 0.55-1.85 | .989 |
| Black/African American × area deprivation quartile 3 | 2.37 | 1.21-4.71 | .013 |
| Black/African American × area deprivation quartile 4 | 0.72 | 0.30-1.71 | .456 |
| Black/African American × Charlson comorbidity index score 2 | 0.54 | 0.24-1.18 | .125 |
| Black/African American × Charlson comorbidity index score 3 | 0.44 | 0.19-0.98 | .046 |
| Black/African American × Charlson comorbidity index score 4 | 0.36 | 0.15-0.81 | .015 |
| Black/African American × Charlson comorbidity index score 5 | 0.43 | 0.17-1.06 | .067 |
| Black/African American × Charlson comorbidity index score ≥ 6 | 0.70 | 0.26-1.91 | .492 |
Model fit statistics: cross-validated area under the receiver operating characteristic curve, 0.561; pseudo R2 = 0.045.
Interaction effect between two variables.