A-C, Line graphs showing longitudinal trends in pulmonary function tests throughout the 24-wk study duration: FEV1 (A), FVC (B), and Dlco (C). Group effect is depicted in blue and individual trends are depicted with red lines. A statistically significant decline in FEV1, but no significant change in FVC or Dlco, was observed. Dlco = diffusing capacity of the lungs for carbon monoxide.