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. 2023 May 24;13:8416. doi: 10.1038/s41598-023-35471-3

Figure 3.

Figure 3

HCoV S1-specific antibody responses of COVID19 mRNA vaccinated health care workers (HCWs). (af) HCoV S1-specific IgG antibody levels were measured with EIA from 339 serum specimens collected before vaccination (0D, Jan/21), and three weeks after second (2D, Feb/21) and third vaccination (3D, Nov/21) from 113 HCWs who received two doses of BNT162b2 with a three-week interval in December 2020 to February 2021 and a third dose of BNT162b2 or mRNA-1273 in September to December 2021. Geometric means and geometric standard deviations of antibody levels are shown. Differences between the groups were analyzed with Wilcoxon matched pairs test. Dashed line indicates the cutoff value for seropositivity. Two-tailed p-values < 0.05 were considered statistically significant. P-values 1111 < 0.0001 and 111 (b) from left to right are 0.0007 and 0.0008.