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Fine mapping of T-cell epitopes on the RSV F protein. Responsiveness of TCC from patients 1 (A) and 2 (B) to partially overlapping 18-mer peptide amides (n = 94) spanning the F protein was measured by an IFN-γ ELIspot assay. Minimal peptide activation of TCC from patients 1 (C) and 2 (D) was measured in an IFN-γ ELIspot assay using APC pulsed with two additional sets of overlapping 8- to 12-mer peptides. med, medium.
