Table 4.
Compound | HBGV | Value | Reference | Comments |
---|---|---|---|---|
PBA and PBA(OH) | ADI | 0.1 mg/kg bw per day | EFSA PPR Panel (2022) | Based upon the overall NOAEL of 100 mg/kg bw per day from the 28‐day studies with PBAld (NOAEL of 98.9 mg/kg bw per day) and PBA(OH) (NOAEL of 106.9 mg/kg bw per day) and UF of 1,000. |
ARfD | 1 mg/kg bw | EFSA PPR Panel (2022) | Based upon the same overall NOAEL and UF of 100. |
ADI: acceptable daily intake; ARfD: acute reference dose; bw: body weight; NOAEL: no observed adverse effect level; UF: uncertainty factor.