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. 2023 May 24;21(5):e08022. doi: 10.2903/j.efsa.2023.8022

Table 4.

Toxicological information on the evaluated pyrethroid metabolites

Compound HBGV Value Reference Comments
PBA and PBA(OH) ADI 0.1 mg/kg bw per day EFSA PPR Panel (2022) Based upon the overall NOAEL of 100 mg/kg bw per day from the 28‐day studies with PBAld (NOAEL of 98.9 mg/kg bw per day) and PBA(OH) (NOAEL of 106.9 mg/kg bw per day) and UF of 1,000.
ARfD 1 mg/kg bw EFSA PPR Panel (2022) Based upon the same overall NOAEL and UF of 100.

ADI: acceptable daily intake; ARfD: acute reference dose; bw: body weight; NOAEL: no observed adverse effect level; UF: uncertainty factor.