FIG. 1.

CTL lytic activity for HIV-infected patients (P1 through P5 and P7) and a representative control (C4). Fresh PBMCs were stimulated for 2 weeks with vP1291 (encoding HIV Gag, Pro, and Env) and mixed with autologous B-lymphocyte cell lines (BLCL) infected with vSC8 (control for Gag), vDK1 (Gag), vP1170 (control for Env), or vP1174 (Env) at the indicated E:T ratios (x axis). The percent release of ⁵¹Cr-labeled targets relative to spontaneous release in a 5-h assay is depicted (y axis). The spontaneous release of ⁵¹Cr was <20% for all experiments.