Table 1.
Amino acid sequences of the intracellular C-terminal region (iCtr) in the different TRESK constructs
| Construct | Amino acid sequence |
|---|---|
| wt | ...FIAFKLVQNRLIDIYKNVMLFFAKGKFYHLVKK |
| Δ374 | ...FIAFKLVQNRLIDIYKNVMLFF |
| Δ366 | ...FIAFKLVQNRLIDI |
| Δ357 | ...FIAFK |
| K356A | ...FIAFALVQNRLIDIYKNVMLFFAKGKFYHLVKK |
| R361A | ...FIAFKLVQNALIDIYKNVMLFFAKGKFYHLVKK |
| K367A | ...FIAFKLVQNRLIDIYANVMLFFAKGKFYHLVKK |
| K356A, R361A | ...FIAFALVQNALIDIYKNVMLFFAKGKFYHLVKK |
| K356E | ...FIAFELVQNRLIDIYKNVMLFFAKGKFYHLVKK |
| R361E | ...FIAFKLVQNELIDIYKNVMLFFAKGKFYHLVKK |
| K356E, R361E | ...FIAFELVQNELIDIYKNVMLFFAKGKFYHLVKK |
| RAADAA | ...FIAFKLVQNRAADAAKNVMLFFAKGKFYHLVKK |
| VMLFF-5A | ...FIAFKLVQNRLIDIYKNAAAAAAKGKFYHLVKK |
| F372L | ...FIAFKLVQNRLIDIYKNVMLLFAKGKFYHLVKK |
| 4K4W2K | ...FIAFKLVQNRLIDIYKNVMLFFAKKKKWWWWKK |
| 12K | ...FIAFKLVQNRLIDIYKNVMLFFAKKKKKKKKKKKK |
| 12N | ...FIAFKLVQNRLIDIYKNVMLFFANNNNNNNNNNNN |
| 12D | ...FIAFKLVQNRLIDIYKNVMLFFADDDDDDDDDDDD |
| 375-6Kcaax | ...FIAFKLVQNRLIDIYKNVMLFFAKKKKKKSKTKCVIM |
| 367-6Kcaax | ...FIAFKLVQNRLIDIYKKKKKKSKTKCVIM |
| 356-6Kcaax | ...FIAFKKKKKKSKTKCVIM |
| RW361 | ...FIAFKLVQNRLLRLLRRLLLWWGKKKKKK |