Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Features associated with the OPTN Glu50Lys mutation.
| OPTN Glu50Lys Mutations in 4 cohorts | ||||
|---|---|---|---|---|
| Instances of Glu50Lys per cohort | 7/52 | 1/105 | 2/132 | 1/67 |
| Inheritance pattern | AD | NA | NA | NA |
| Penetrance | 70.40% | NA | NA | NA |
| IOP data (mm Hg) | 81.6% had IOP < 21 | NA | NA | Mean Max IOP = 16 |
| References | Rezaie et al, 2002 | Alward et al, 2003 | Aung et al, 2003 | Hauser et al 2006 |
AD: autosomal dominant, NA: Not available.
