Table 1.
ROC characteristics of individual parameters.
| AUC (95% CI) | Sensitivity | Specificity | cut off1,2 | |
|---|---|---|---|---|
| GLCM | ||||
| Autocorrelation | 0.693 (0.621-0.729) | 0.49 | 0.88 | ≤370 |
| ClusterProminence | 0.649 (0.575-0.717) | 0.56 | 0.74 | ≤33077 |
| ClusterShade | 0.589 (0.514-0.660) | 0.75 | 0.52 | > -190 |
| ClusterTendency | 0.652 (0.579-0.720) | 0.54 | 0.79 | ≤111 |
| Correlation | 0.695 (0.624-0.761) | 0.86 | 0.47 | ≤0.68 |
| GLCMEntropy | 0.617 (0.542-0.687) | 0.60 | 0.64 | ≤7.9 |
| Homogeneity2 | 0.586 (0.511-0.658) | 0.60 | 0.61 | > 0.25 |
| InformationMeasureCorrl | 0.653 (0.580-0.722) | 0.37 | 0.90 | > -0.23 |
| InformationMeasureCorr2 | 0.666 (0.594-0.734) | 0.55 | 0.71 | ≤0.93 |
| InverseDiffMomentNorm | 0.607 (0.532-0.677) | 0.69 | 0.55 | > 0.99 |
| InverseDiffNorm | 0.601 (0.526-0.672) | 0.71 | 0.53 | > 0.93 |
| SumAverage | 0.690 (0.618-0.756) | 0.43 | 0.93 | ≤34 |
| SumEntropy | 0.649 (0.576-0.718) | 0.54 | 0.75 | ≤5.23 |
| SumVariance | 0.695 (0.623-0.760) | 0.50 | 0.87 | ≤1163 |
| GLCMVariance | 0.652 (0.579-0.720) | 0.53 | 0.79 | ≤111 |
| GLRLM | ||||
| HighGrayLevelRunEmphasis | 0.692 (0.620-0.758) | 0.50 | 0.86 | ≤403 |
| LongRunHighGrayLevelEmphasis | 0.705 (0.634-0.770) | 0.53 | 0.90 | ≤1120 |
| LongRunLowGrayLevelEmphasis | 0.710 (0.639-0.774) | 0.46 | 0.93 | > 0.01 |
| LowGrayLevelRunEmphasis | 0.709 (0.637-0.773) | 0.46 | 0.97 | > 0.005 |
| RunLengthNonUniformity | 0.622 (0.548-0.692) | 0.78 | 0.50 | ≤752 |
| ShortRunEmphasis | 0.594 (0.520-0.666) | 0.94 | 0.27 | ≤0.93 |
| ShortRunHighGrayLevelEmphasis | 0.691 (0.619-0.756) | 0.41 | 0.96 | ≤ 224 |
| ShortRunLowG rayLevelEmphasis | 0.714 (0.643-0.778) | 0.47 | 0.97 | > 0.003 |
| First Order | ||||
| Energy | 0.681 (0.609-0.747) | 0.60 | 0.78 | ≤308210827 |
| GlobalEntropy | 0.613 (0.539-0.683) | 0.51 | 0.75 | ≤4.8 |
| GlobalMax | 0.657 (0.584-0.725) | 0.46 | 0.89 | ≤ 591 |
| GlobalMean | 0.690 (0.618-0.756) | 0.50 | 0.87 | ≤379 |
| GlobalMedian | 0.691 (0.619-0.757) | 0.49 | 0.89 | ≤375 |
| GLobalMin | 0.718 (0.647-0.782) | 0.53 | 0.88 | ≤144 |
| GlobalStd | 0.629 (0.555-0.698) | 0.53 | 0.76 | ≤130 |
| GlobalUniformity | 0.613 (0.539-0.684) | 0.55 | 0.71 | > 0.03 |
| Kurtosis | 0.616 (0.542-0.686) | 0.70 | 0.53 | > 1.95 |
| LocalEntropyMax | 0.600 (0.525-0.671) | 0.42 | 0.83 | ≤4.5 |
| LocalEntropyStd | 0.636 (0.562-0.705) | 0.76 | 0.50 | ≤0.42 |
| MeanAbsoluteDeviation | 0.630 (0.556-0.700) | 0.51 | 0.77 | ≤105 |
| 10Percentile | 0.712 (0.641-0.776) | 0.43 | 0.97 | ≤179 |
| 25Percentile | 0.701 (0.630-0.766) | 0.43 | 0.97 | ≤240 |
| 50Percentile | 0.691 (0.619-0.757) | 0.50 | 0.89 | ≤375 |
| 75Percentile | 0.685 (0.612-0.751) | 0.48 | 0.89 | ≤471 |
| 90Percentile | 0.676 (0.604-0.743) | 0.52 | 0.85 | ≤569 |
| Range | 0.610 (0.535-0.680) | 0.50 | 0.78 | < 487 |
| RootMeanSquare | 0.687 (0.615-0.753) | 0.48 | 0.89 | < 396 |
| Skewness | 0.623 (0.548-0.693) | 0.46 | 0.78 | > 0.10 |
| Variance | 0.629 (0.555-0.698) | 0.53 | 0.77 | <16975 |
| NGTDM | ||||
| Busyness | 0.682 (0.610-0.748) | 0.52 | 0.86 | > 0.024 |
| Complexity | 0.597 (0.522-0.688) | 0.40 | 0.84 | < 67825 |
| TextureStrength | 0.618 (0.544-0.688) | 0.54 | 0.68 | < 236 |
1For diagnosis of irreversible bone marrow lesions
2Determined according to Youden index