Skip to main content
. 2023 Apr 12;1(2):121–139. doi: 10.1021/cbmi.3c00019

Figure 12.

Figure 12

3T D2O MRI can guide the intervention for the hyperosmotic opening of BBB in a dog. (A) T2w image preinjection. (B) D2O MRI contrast-enhancement map. (C) SPIO MRI contrast-enhancement map. (D) Gd-contrast-enhancement map after the administration of mannitol. (E) Correlation between SPIO- and D2O-MRI. The Spearman coefficient (r) = 05350. (F) Correlation between Gd- and D2O- MRI. The Spearman coefficient (r) = 0.6009. Reprinted with permission from ref (142). Copyright 2021 Ivyspring International Publisher.