Table 3.

Association between early thromboprophylaxis and mortality by admission diagnosis

Characteristic	Odds ratios (95% CI)	P-value
Overall
Thromboprophylaxis status
Yes	Ref
No	1.35 (1.31–1.40)	< 0.001
Contraindicated	1.35 (1.31–1.40)	< 0.001
Not indicated	1.22 (0.94–1.12)	0.522
Admission diagnosis
Head trauma (with or without multi trauma) (n = 15,618)
Yes	Ref
No	1.23 (0.97–1.56)	0.090
Contraindicated	1.20 (0.95–1.51)	0.115
Not indicated	1.71 (1.08–2.69)	0.020
Cardiac arrest (n = 29,498)
VTE prophylaxis
Yes	Ref
No	1.85 (1.65–2.07)	< 0.001
Contraindicated	1.37 (1.16–1.62)	< 0.001
Not indicated	1.29 (1.91–2.75)	< 0.001
Intracerebral haemorrhage (n = 7,448)
Yes	Ref
No	1.48 (1.19–1.84)	< 0.001
Contraindicated	1.14 (0.96–1.37)	0.136
Not indicated	2.41 (1.52–3.82)	< 0.001
Subarachnoid haemorrhage (n = 6,598)
Yes	Ref
No	1.09 (0.79–1.50)	0.582
Contraindicated	0.97 (0.74–1.26)	0.824
Not indicated	1.38 (0.73–2.59)	0.316
Stroke (n = 11,615)
Yes	Ref
No	1.26 (1.05–1.52)	0.014
Contraindicated	1.07 (0.90–1.27)	0.457
Not indicated	1.16 (0.82–1.63)	0.392

Adjusted for Australian and New Zealand Risk of Death (ANZROD). ANZROD is derived from patient and clinical characteristics, including the Acute Physiology and Chronic Health Evaluation (APACHE) III, ICU admission source, admission diagnoses, Acute Physiology score (APS), APACHE III chronic health score, treatment limitation, and ventilation status. VTE-Venous thromboembolism