Table 1.
Results from triaging with cytology, genotyping and methylation
| Triage test | hrHPV pos, n | Triage test pos, n | Normal histo, n | LSIL histo, n |
NPV ≥LSIL |
PPV ≥LSIL |
FNR ≥LSIL |
HSIL histo, n |
NPV ≥HSIL |
PPV ≥HSIL |
FNR ≥HSIL |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cytology | 49 | 12 | 7 | 0 | 0.73 | 0.42 | 67 | 5 | 0.95 | 0.42 | 29 |
| Genotyping | 49 | 30 | 20 | 4 | 0.74 | 0.33 | 33 | 6 | 0.95 | 0.2 | 14 |
| Methylation | 48 | 35 | 24 | 6 | 0.69 | 0.31 | 27 | 5 | 0.85 | 0.14 | 29 |
Abbreviations: hrHPV, high-risk HPV; histo, histology; LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion; NPV, negative predictive value; PPV, positive predictive value; FNR, false negative rate.