Table 1.
Basic clinical parameters and pregnancy outcomes of three study groups
| Group A | Group B | Group C | P-value (A vs. B) | P-value (A vs. C) | |
|---|---|---|---|---|---|
| N | 75 | 66 | 258 | ||
| Female age (year) | 30.4 ± 4.3 | 30.2 ± 4.8 | 31.1 ± 4.0 | 0.585 | 0.310 |
| Male age (year) | 33.2 ± 6.1 | 32.8 ± 5.9 | 33.3 ± 5.3 | 0.679 | 0.895 |
| Body mass index (BMI, kg/m2) | 21.0 ± 2.6 | 21.1 ± 2.7 | 20.9 ± 2.7 | 0.478 | 0.910 |
| Type of infertility (n (%)) | 0.851 | 0.834 | |||
| Primary | 42 (56.0) | 38 (57.6) | 148 (57.4) | ||
| Secondary | 33 (44.0) | 28 (42.4) | 110 (42.6) | ||
| Duration of infertility (year) | 2.3 ± 1.2 | 2.4 ± 1.1 | 2.9 ± 2.1 | 0.298 | 0.017* |
| Basal FSH (mIU/ml) | 6.5 ± 1.9 | 6.4 ± 2.2 | 6.5 ± 2.0 | 0.919 | 0.903 |
| No. of dominant follicles > 16 mm | 1.0 ± 0.2 | 1.6 ± 0.6 | 1.0 ± 0.1 | 0.000* | 0.186 |
| Endometrium thickness (mm) | 10.1 ± 1.7 | 10.0 ± 1.9 | 10.1 ± 1.6 | 0.724 | 0.969 |
| Total progressive motile sperm count (post-wash) | 19.3 ± 11.4 | 22.4 ± 13.1 | 18.3 ± 11.2 | 0.243 | 0.512 |
| Normal morphology (%, post-wash) | 4.7 ± 1.9 | 4.8 ± 1.6 | 4.4 ± 1.9 | 0.394 | 0.160 |
| tubal occlusion site | 0.497 | / | |||
| proximal tubal occlusion | 53 (70.7) | 50 (75.8) | / | ||
| mid-distal or distal tubal occlusion | 22 (29.3) | 16 (24.2) | / | ||
| Clinical pregnancy (n (%)) | 7 (9.3) | 6 (9.1) | 28 (10.9) | 0.960 | 0.706 |
| Live birth (n (%)) | 4 (5.3) | 4 (6.1) | 25 (9.7) | 1.000 | 0.239 |
| First trimester miscarriage (n (%)) | 3 (42.9) | 0 (0) | 2 (7.1) | 0.192 | 0.044* |
Group A: IUI without ovarian stimulation (OS) in patients with unilateral tubal occlusion; Group B: IUI with OS in patients with unilateral tubal occlusion; and Group C: IUI without OS cycle in patients with bilateral patent tubes. Values are presented as mean ± standard deviation or n (%)
*P < 0.05 was considered statistically significant